Translational Data Scientist

  • Novartis
  • Basel, BS, Switzerland
  • 31/05/2019
Full time Data Science Machine Learning Data Analytics Statistics

Job Description

As a member of the Quantitative Sciences & Innovation (QSI) unit in Biomarker Development, you will join Novartis’ clinical trial teams to speed new medicines into the clinic across one of the industry’s largest and most innovative portfolios. By integrating large-scale genomic and biomarker profiles from First In Human through Phase III clinical trials, you will investigate disease heterogeneity, drug efficacy, and patient safety at molecular resolution to advance trials in new indications and patient populations. You are passionate and curious scientist, eager to bring creative solutions to biology’s most daunting challenges on our journey to reimagine medicine. Working alongside dedicated physicians and biomarker scientists, our Investigators provide the analytical insights that drive Translational success.

Your responsibilities will include:

  • Conceive, design, and execute exploratory analyses as Lead Biomarker Analyst within First In Human, Phase I-III clinical trials, applying advanced analytical methods as required
  • Provide Statistical Genetics subject matter expertise and analysis solutions to inform patient stratification and enrichment strategies
  • Participate in and lead cross-functional biomarker collaborations with Discovery and Development partners to support target selection and registration activities
  • Work expeditiously as a member of matrixed clinical trial teams with diverse membership and expertise

Minimum requirements

What you’ll bring to the role:

  • PhD or MD or equivalent experience in statistical genetics, bioinformatics, biostatistics, computational biology, machine learning, data science or related field
  • Three or more years of experience in analyzing large biological datasets in a drug discovery/development or relevant academic setting
  • Expert knowledge of statistical programming in R. Working experience with Python or similar scripting programming language a must
  • Expertise in human genetics or molecular epidemiology, with a strong grasp of genomic approaches, technologies, and analytics to inform clinical trial design and enrichment, e.g. GWAS/RVAS/PheWAS.
  • Experience with causal inference and/or graphical methods highly desirable, e.g. Mendelian Randomization
  • Solid understanding of biostatistics and machine learning


WHY CONSIDER NOVARTIS?
750 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are empowered to ask new questions, make bolder decisions and take smarter risks.

We are Novartis. Join us and help us reimagine medicine.

Division

NIBR

Business Unit

Translational Medicine

Country

Switzerland

Work Location

Basel

Company/Legal Entity

Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full Time

Employment Type

Regular